Synthesis of Hydrophilic Crosslinked Poly(vinyl alcohol)s Comprising Poly(ethylene glycol) as a Crosslinker

Polyethylene glycol as a cause of anaphylaxis

BACKGROUND Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. CASE REPORT We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick tests, intradermal tests (IDT) and a double-blind oral challenge was performed to...

Synthesis and Characterization of Polyethylene Glycol Dinitrates

Polyethylene glycol dinitrates (PEGN) with molecular weights between 400 and 20 000 g·mol-1 were prepared from polyethylene glycols by esterification with nitric acid/sulfuric acid in dichloromethane. The products were characterized by gel permeation chromatography. The yield of PEGN increases with increasing reaction temperature (0-40 °C) however large liberation of nitrogen oxides was observe...

Surface Adsorption of Polyethylene Glycol and Polyvinyl Alcohol with Variable Molecular Weights on Zinc Oxide Nanoparticles

Angiogenic competency of biodegradable hydrogels fabricated from polyethylene glycol-crosslinked tyrosine-derived polycarbonates.

Synthetic biomaterials can be used as instructive biological milieus to guide cellular behaviour and function. To further realize this application, we synthesized a series of structurally similar hydrogels and tested their ability to modulate angiogenesis. Hydrogels were synthesized from poly(DTE-co-x% DT carbonate) crosslinked by y% poly(ethylene glycol) (PEG). Hydrogel desaminotyrosyl tyrosin...

Polyethylene glycol embedded tribromide as an efficient and reusable catalyst for the library synthesis of nitrogen containing heterocycles

Potassium tribromide wrapped around polyethylene glycol ({K+PEG400}Br3-) was easily prepared by two step reaction of PEG400 with KBr followed by the addition of molecular bromine to give PEG embedded potassium tribromide as a dark viscous oil. The synthesized material was found to be an efficient, cost effective, environmentally benign and recyclable catalyst for the library synthesis of nitrog...